In our latest question and answer, the pharmacist discusses even if it is or no it is safe to take NyQuil and also azithromycin (Z-Pak) together.

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TJS asked

I began with my an initial dose that Azithromycin today, two 250mg roughly 6hours ago. Can I take it Nyquil tonight prior to bed.


There are no drug interactions between azithromycin (Z-pak)and Nyquil (acetaminophen, dextromethorphan, and doxylamine). They can be safely bring away together. Below, we willdiscuss much more about the 2 medications.

Information about TheZ-Pak

A Z-pak is composed of 6 tablets that azithromycin 250 mg.Usually 2 tablets room prescribed ~ above the first day the therapy, followed by onetablet for the adhering to four days.

Azithromycinis a macrolide antibiotic that deserve to treat a selection of epidemic includingbronchitis, sinus infections, ear infections, skin infections, sexuallytransmitted infections, and more. Azithromycin can cover several varieties ofbacteria, yet is not efficient intreating the flu, the typical cold, or other viral infections.

Like many antibiotics, azithromycin may reason diarrhea,nausea, vomiting, and abdominal muscle pain. Macrolides are more likely to cause thesetypes of next effects, but azithromycin is one of the an ext tolerable medicine inthe class. Another concern v azithromycin is the it can reason QTprolongation in patients through a previous medical history related to the heart. Druginteractions can likewise be a worry so constantly check each brand-new medication former tostarting a new therapy.

Information AboutNyquil

Nyquil comes in avariety the formulations and contains several various ingredients. Nyquil Cold& Flu contains the following:

Acetaminophen (pain relief, fever reducer)Dextromethorphan (cough suppressant)Doxylamine (antihistamine)

Acetaminophen is an analgesic that can be taken for a widevariety that acute and chronic ache ailments. Acetaminophen has actually a half-life of2-3 hours. Acetaminophen gets took in at 85-98% and also reaches peak concentrations within 30-60 minutes.Typically, acetaminophen have the right to startworking within 15 minutes. Acetaminophen deserve to have an unfavorable impacts ~ above theliver, particularly at higher doses for an extended period of time.

Dextromethorphan (commonly described as DM on manyover-the-counter products) is a coughsuppressant that to reduce the advice to cough. It is ideal to preventbothersome dry cough or a sneeze that no involve mucus from the lowerrespiratory system.

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Doxylamine is a first-generation antihistamine the is morelikely to cause sedation and drowsinessas contrasted to second-generation antihistamines (i.e. Loratadine, cetirizine). Otherfirst-generation antihistamines encompass Benadryl (diphenhydramine), Dramamine(dimenhydrinate), Chlor-Trimeton (chlorpheniramine), Tavist (clemastine), andPhenergan (promethazine), amongst others.